A group of researchers from Singapore are exploring the question what’s the longest life that could be lived by a human system. The researchers from Singapore-based biotech company Gero point to an underlying “pace of ageing” that sets the lifespan between 120-150 years.
In the journal which is named as “Longitudinal analysis of blood, markers reveal progressive loss of resilience and predict human lifespan limit and that death is an intrinsic biological property that is independent of stress factors.
To assess this evolution, the researchers looked at changes in blood cell counts and the daily number of steps taken by people. They looked at health data for large groups from the US, the UK and Russia. Ageing in humans exhibits universal features common to complex systems operating on the brink of disintegration.
Led by Timothy V Pyrkov, the team observed that as age increased, the factors beyond disease drove a predictable and incremental decline in the body’s ability to return blood cells. They found that the pace of decline determined when that resilience will completely disappear leading to death. They found that age of complete resilience loss at the range of 120 to 150 years.
The more interesting observation of the research included the fact that resilience starts declining steeply somewhere in the mid-thirties to mid-forties with the body slowly losing its ability to cope and recover from stress. The team observed that as age increased the factors beyond disease drove a predictable and incremental decline.
Experts believe that the research could guide the development of drugs to slow the process and extend healthspan as recovery rate is an important sign of ageing.
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