According to a study by the US Center for Disease Control and Prevention (CDC) people who are not vaccinated against Covid-19 are two times more likely to be re-infected with the deadly infectious disease.
The study stated that being unvaccinated was associated with 2.34 times the odds of re-infection compared with being fully vaccinated and to reduce their likelihood for future infection, all eligible persons should be offered Covid-19 vaccine, even those with previous SARS-CoV-2 infection.
Although laboratory evidence suggests that antibody responses following Covid-19 vaccination provide better neutralisation of some circulating variants than does natural infection, few real-world epidemiologic studies exist to support the benefit of vaccination for previously infected persons, the CDC said.
Further, the study also acknowledges its limitations, such as re-infection was not confirmed through whole-genome sequencing, which would be necessary to definitively prove that the re-infection was caused by a distinct virus relative to the first infection; and that people who have been vaccinated are possibly less likely to get tested and thus the link between re-infection and lack of vaccination might be overestimated.
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