According to a study by the All India Institute of Medical Sciences (AIIMS) Delhi, the presence of antibodies, or seroprevalence, against coronavirus was found to be lower among HIV/AIDS-infected people.
As per the report, the study was conducted on around 164 people living with HIV/AIDS (PLHAs) whose mean age was 41.2 years, recruited from the Anti-Retroviral Therapy (ART) centre at AIIMS between September 1 and November 30, 2020.
While the observational study is yet to be peer-reviewed but was found that antibody prevalence to be 14 per cent among those 164 people. As per the study, a total of 164 patients were recruited in the study with mean age (+SD) of 41.2 (+15.4) years and 55 per cent male population. Positive serology against SARS CoV-2 was detected in 14 per cent of patients (95 per cent C 9.1-20.3 per cent). The seroprevalence of COVID-19 disease in PLHA was found to be lower than the general population.
There were 23 participants (14 per cent) who were seropositive for SARS-CoV-2. And most of them experienced minimal or no COVID-19 symptoms. When samples from HIV/AIDS-infected people were collected, the average seropositivity in Delhi was 25.7 per cent.
The researchers stated that one of the main reasons for low prevalence could be that most of the patients were indoors and avoid social contact, and may not have actually contacted the disease. While another reason could be that these patients might not have generated antibodies against COVID-19 or may not have sustained it after getting infected.
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