A researcher is never off duty. Moreover, if the researcher is in the medical field, then his/her analysis and experimentation are for the cure and treatment for millions of people. That is what Dr. Jhansee Mishra is doing for years. Interview Times had a great opportunity to converse with the stalwart researcher Dr. Jhansee Mishra and know more about the medicines and the medical field.
This is how the Interview went-
Can you Brief about yourself to our readers?
Namaskar, everyone. First of all, I would like to thank Interview Times for showing interest in covering my interview.
I am Dr. Jhansee Mishra, a proud Indian born and raised in Bhubaneswar, Odisha, India. I received my B—Pharm, M.Pharm & Ph.D. degrees from the different renowned universities of India. Currently, I am working as an Assistant Professor at the Institute of Pharmacy, V.B.S.Purvanchal University, India.
My current research projects are focused on “ Polyherbal formulation and standardization of selected few medicinal plant having antidiabetic activity.” Phytopharmacological work on active isolated constituents from Indian folklore medicine focused on exploring their therapeutic potential and attempting to formulate a standardized product by following the modern herbal Ayurvedic monographs and international guidelines.
I also try to spread my scientific knowledge in many national and international journals by quality research works. My research field focuses on the formulation of herbal drugs, Pharmacognosy, pharmacological screening and standardization method development for herbals. I have more than 30 National and International publications and four books to my credit.
I attended the “6th Edition of the International Conference on Pharmacognosy and Medicinal Plants during April 16-17, 2018, in Amsterdam, Netherlands, and received the Young scientist award. Also, I have been invited as a guest in the daily Odia T.V. show Breakfast Odisha in NEWS-7. Moreover, I have shared my research output at Big F.M. 92.7.
I am also working as an editor of many reputed national and international journals. I serve as a life member of different associations of pharmacy in India. Also, I have delivered many talks at national and international conferences.
Were you inclined towards the medical field since childhood, or was it from an influence of a role model?
Yes, it was since childhood that I was inclined towards the field of medicines. Surely, then, I did not have this thorough knowledge. However, I always said that I wanted to become a doctor.
As I grew up, my inclination towards the medical science field enhanced more. Therefore, I pursued it as a professional career. Today, I feel lucky enough to be in the medical field and serve millions of people through my research.
Can you brief us more about your current research work?
Yes, currently I am working on the following research paper-
Development and evaluation of Polyherbal antidiabetic Fast dissolving Tablet
Polyherbal extracts of Azadirachta indica (neem), Camellia sinensis (green tea), Asparagus racemosus( Shatavari), i.e., the best formulation F1 (N: G S=2:2:1) are prepared and converted into fast dissolving tablets using super disintegrant by direct compression method.
Those tablets were evaluated for weight variation, hardness, disintegration time, drug content, friability and stability study. A stability study was also conducted as per ICH guidelines, and all formulations were found to be stable. The results concluded that F.D.T. of neem will leads to improved effectiveness and hence better patients’ compliances.
Recent advances in gastro retentive drug delivery system
Gastro retentive drug delivery system is an approach to prolong gastric residence time, thereby targeting site-specific drug release in the upper gastrointestinal tract improving the sustained oral delivery of a drug with an absorption window in a particular region the gastrointestinal tract.
These systems continuously release the drug before it reaches the absorption window, thus ensuring optimal bioavailability. Various approaches for gastric retention are Floating system, Swelling and expanding system, Bioadhesive systems, Modified-shape systems, High-density systems, etc.
Hypoglycemic, hypolipidemic, and antioxidant potentials of specially formulate Polyherbal, Formulation in streptozotocin-induced diabetic rats
To investigate the antihyperglycemic, hypolipidemic and antioxidant properties of the specially formulate polyherbal Formulation in Streptozotocin-induced diabetic rats. Multifactorial metabolic diseases, such as diabetes, develop several complications like hyperlipidemia, hepatic toxicity, immunodeficiency, etc.
Instead of mono-drug therapy, the management of the disease requires a combination of herbs. Marketed herbal drugs comprise irrational combinations, which makes their quality control more difficult. Phytoconstituents, despite having excellent bioactivity in vitro, demonstrate less or no in vivo actions due to their poor lipid solubility, resulting in a high therapeutic dose regimen.
Nanotechnology Challenges; Nanomedicine: Nanorobots
Nanotechnology, as a diagnostic and treatment tool for patients with cancer and diabetes, showed how actual developments in new manufacturing technologies enable innovative works, which may help in constructing and employing nanorobots most effectively for biomedical problems.
Nanorobots applied to medicine hold a wealth of promise, from eradicating disease to reversing the ageing process (wrinkles, loss of bone mass, and age-related conditions are all treatable at the cellular level); nanorobots are also candidates for industrial applications.
Formulation and in-vitro characterization of chitosan-nanoparticles loaded with ciprofloxacin hydrochloride
Prepare the nanoparticles by using Ciprofloxacin Hcl was used as a model drug. In this work, different drug and polymer ratios were used. The prepared formulations were subjected to additional in-vitro analyses such as drug content analysis, particle size analysis, zeta potential analysis, and in-vitro drug release and stability studies.
The particle size is about 457 nm; the drug content is in the range of 56 + 0.12 to 68 + 0.13. The zeta potential was 38.6 mv. The cumulative percentage of drug release was about 85 %. F2 formulation was found to be the best formulation with a higher cumulative rate of drug release.
Can you site us the importance of Ayurvedic and herbal medicines and the harmful effects of Allopathy?
Ayurvedic medicines have a long history and can be rooted back thousands of years ago to the ancient Indian culture. It has greater patience tolerance. It has very few side-effects. Moreover, it is used for the treatment of chronic diseases. (Mostly Used). However, Ayurvedic medicines are sometimes a bit expensive.
Allopathy medicines have more toxins value. Moreover, they may be harmful side effects and are expensive as well. However, they can assure you of an early cure.
From my point of view, both Ayurvedic and Allopathy are two aides of the same coin. If someone suffers from chronic disease, he/she should opt for Ayurvedic, and if someone is suffering from a mild health issue, he/she should opt for Allopathy.
Can Ayurveda help us in immunity-boosting and protection from Corona until we get the vaccine?
Not only Ayurveda, try different organic techniques to boost your immunity.
As the world is fighting hard against CO-VID and there are still no signs of a legitimate vaccine for at least six months, one should always try to boost your immunity with daily exercise, good food, and intake of herbal and ayurvedic medicines.
In my view, not only medicines but herbs like Tulsi, Cinnamon, and exercises like Yoga are the major catalysts to boost one’s immunity.